CoDAS
https://codas.org.br/article/doi/10.1590/2317-1782/20212020300
CoDAS
Artigo Original

Efeito inibitório da via auditiva eferente na síndrome de Turner

Efferent Auditory Pathways Inhibition in Turner syndrome

Martha Marcela de Matos Bazilio; Adriana Fernandes Duarte dos Santos; Silvana Frota; Marília Guimarães; Márcia Gonçalves Ribeiro

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Resumo

Objetivo: investigar o efeito inibitório da via auditiva eferente na síndrome de Turner e relacionar com o perfil citogenético. Método: estudo descritivo transversal com grupo de comparação. Amostra: Grupo estudo formado por 40 pacientes com síndrome de Turner (17,6 anos); e Grupo controle constituído por 54 indivíduos (18,9 anos), do sexo feminino sem síndrome. Os indivíduos selecionados foram submetidos à pesquisa do efeito inibitório da via auditiva eferente. Resultados: A média do Efeito inibitório da via auditiva eferente no grupo estudo na orelha direita foi 0,4 dB e no grupo comparação foi de 1,9 dB, entretanto na orelha esquerda a média do efeito inibitório da via auditiva eferente foi 1,4 dB no grupo estudo e 0,8 dB no grupo comparação. O efeito inibitório da via auditiva eferente foi presente em 14 indivíduos com monossomia e em 15 com outras alterações citogenéticas. Conclusão: No grupo estudo o valor do efeito inibitório da via auditiva eferente foi significantemente maior na orelha esquerda e significativamente menor que o grupo controle na direita. Não houve diferença significativa no efeito inibitório da via auditiva eferente entre os tipos de cariótipo.

Palavras-chave

Síndrome de Turner; Disgenesia Gonadal 45X; Via Eferente; Complexo Olivar Superior; Emissões Otoacústicas

Abstract

Purpose: The goal of this study is to investigate the efferent auditory pathways inhibition in Turner’s syndrome and to relate it to the cytogenetic profile. Methods: This is a cross-sectional study with a comparison group. A sample with 94 participants divided into two groups: The study group was a sample of 40 patients diagnosed with Turner’s syndrome (17.6 years of age). The control group was composed of 54 volunteers (18.9 years of age), female, without syndrome. The selected individuals were submitted to efferent auditory pathways inhibition research. Results: The mean of the inhibitory effect of the efferent auditory pathway in the study group in the right ear was 0.4 dB and in the comparison group it was 1.9 dB, however in the left ear the mean of the inhibitory effect of the efferent auditory pathway was 1.4 dB in the study group and 0.8 dB in the comparison group. The inhibitory effect of the efferent auditory pathway was present in 14 individuals with monosomy and in 15 with other cytogenetic alterations. Conclusions: In the study group, the efferent auditory pathways inhibition value was significantly higher in the left ear and significantly lower than the control group in the right ear. There was no significant difference in efferent auditory pathways inhibition of right ear and left ear between the karyotype types

Keywords

Turner Syndrome; XO Gonadal Dysgenesis; Efferent pathways; Superior olivary complex; Otoacoustic emissions

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Aceito em:
04/02/2021

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